The Binding of Isaac: Four Souls STRATEGY and you may play one

and you may play one or more adventures in a game session

The Pillbug may not move a piece through a too-narrow gap of stacked pieces (violating the Freedom to Move Rule)

and both LTPK Sets may be used together in any order

It’s the central character and the only one to advance via XP

Being cursed forces a player to take the Cursed card and roll the black die along with the rest of his dice pool

The Binding of Isaac: Four Souls STRATEGY and you may play oneThe official Binding of Isaac multiplayer card game, about sacrifice, betrayal and hoarding. 2 4 players take turns playing loot cards and using items to kill monsters that yield more items, loot, and sometimes souls. The first player to end their turn with 4 souls is the winner. Cooperation, barter, and betrayal is encouraged.