70nm Carboxyl (carboxyl-PEG5000-SH) Gold Nanoparticles Water Soluble Iron Oxide Nanoparticles Surface functionality: Maleimide (~1 Maleimide

Surface functionality: Maleimide (~1 Maleimide group/nm2) (10kDa PEG-spacer between gold surface and Maleimide-group)

100nm NHS-Activated Gold NanoUrchins (lyophilized) - 1 vial

(M-1cm-1) Size Dispersity (+/-nm) Particle Volume (nm3) Surface Area (nm2) Surface/Volume Ratio Particle Mass (g) Molar Mass (g/mol) Molar Concentration* 60 585 1

Illustration of the appearance of the Miriad™ cartridge after applying a gold conjugate (conjugated to an antibody against the antigen of interest) when target is present (left) and not present in the sample (right)

Our Gold NanoUrchins are unique spherical gold nanoparticles with spiky protrusions

70nm Carboxyl (carboxyl-PEG5000-SH) Gold Nanoparticles Water Soluble Iron Oxide Nanoparticles Surface functionality: Maleimide (~1 MaleimideComposition: Carboxyl gold nanoparticles Core Size: 70nm Absorption max: 548nm Optical Density (OD): 50 Particles per ml: 6. 00E+11 Carboxyl Surface Density: ~1 nm2 Formulation: Supplied in USP grade purified water Properties Cytodiagnostics PEGylated Gold Nanoparticles with carboxyl functional groups are made using a unique proprietary protocol resulting in particles with superior size distribution and shape compared to the leading competitor and are